Validity of the New Definitions of Hypoglycaemia

Hypoglycaemia is a feared complication of glucose lowering agents in the treatment of diabetes. New treatments need to be judged not just for their ability to lower glucose, and for their potential impact on long term complications, but also for their risk for causing hypoglycaemia. It is therefore essential to have a meaningful and standard definition for hypoglycaemia that can be uniform across studies and is also useful clinically. The International Hypoglycaemia Study group reviewed the literature and proposed a revised definition that has been adopted with  minor modification by international diabetes bodies, including those with a patient voice. Although the scheme was originally proposed specifically for use in Clinical trials and for regulators to consider, the definitions are also useful in clinical management of diabetes